Dr. Ned Sharpless has served as the director of the National Cancer Institute since October 2017. Previously, Dr. Sharpless served as Acting Commissioner of the U.S. Food and Drug Administration, director of the University of North Carolina Lineberger Comprehensive Cancer Center and on the faculty of Harvard Medical School. Dr. Sharpless earned his medical degree from UNC and completed his internal medicine residency at Massachusetts General Hospital and a hematology/oncology fellowship at Dana-Farber and Partners Cancer Care.
Dr. Sharpless is a member of the Association of American Physicians as well as the American Society for Clinical Investigation (ASCI), the nation’s oldest honor society for physician–scientists. He served on the ASCI council from 2011 to 2014. Dr. Sharpless has written more than 150 original scientific papers, reviews and book chapters and holds 10 patents. He co-founded two clinical-stage biotechnology companies: G1 Therapeutics and HealthSpan Diagnostics. In addition to serving as director of NCI, Dr. Sharpless is chief of the Aging Biology and Cancer Section in the National Institute on Aging’s Laboratory of Genetics and Genomics, where he continues his research on the biology of the aging process that promotes the conversion of normal self-renewing cells into dysfunctional cancer cells. Dr. Sharpless has made pivotal contributions to the understanding of the relationship between aging and cancer, and in the preclinical development of novel therapeutics for melanoma, lung cancer and breast cancer.